Learn what's happening in your body
during each phase & the research behind
every single ingredient in our
hormone-supportive blends.
during each phase & the research behind
every single ingredient in our
Formulated to the phase, not around it.
One tea can't serve your whole cycle. Four blends, each timed to a different hormonal shift.
Transparent, ingredient by ingredient.
Tap into any ingredient below to see the exact study behind it, the sample size, and where the evidence stands.
Flow Tea
This is for when you're feeling crampy, exhausted, and just done. That's real, and it's not random: your body releases prostaglandins, tiny chemical messengers that basically tell your uterus to squeeze (rude, we know), and that's what causes the cramping. Flow tea is here to make the roughest days feel a little softer.
Ginger Root
A 2024 meta-analysis pooling 12 clinical trials found ginger significantly reduced both the intensity and duration of period pain compared with placebo, performing comparably to NSAIDs for pain intensity.
Why here: ginger targets the prostaglandin-driven cramping that peaks in the first days of your period, which is exactly when Flow tea is meant to be used.
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According to PubMed: Moshfeghinia et al., J Integr Complement Med 2024, DOI: 10.1089/jicm.2023.0799
Chamomile
A randomized, double-blind, placebo-controlled trial in 57 adults found chamomile extract produced a significantly greater reduction in anxiety scores than placebo over 8 weeks (P = 0.047).
Why here: chamomile eases the pain-linked anxiety and restlessness that can make the first days of your period harder to get through, and supports the rest your body needs while it's actively shedding the uterine lining.
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According to PubMed: Amsterdam et al., J Clin Psychopharmacol 2009, DOI: 10.1097/JCP.0b013e3181ac935c
Raspberry Leaf
Raspberry leaf has a long history of traditional use for uterine tone. Systematic reviews of the available research describe the clinical evidence as still preliminary, a biological effect on uterine muscle has been observed in laboratory and pregnancy studies, but controlled trials in the general cycling population are limited.
Why here: traditionally used to support healthy uterine muscle tone during active bleeding, which is the physiological center of the menstrual phase.
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According to PubMed: Socha et al., Nutrients 2023, DOI: 10.3390/nu15143206; Bowman et al., BMC Complement Med Ther 2021, DOI: 10.1186/s12906-021-03230-4
Orange Peel
Orange peel is rich in hesperidin, the citrus flavonoid most studied for its antioxidant and anti-inflammatory activity. Review literature supports its role in a healthy inflammatory response, drawn largely from liver and metabolic research.
Why here: adds gentle antioxidant and anti-inflammatory support while your body sheds and begins repairing the uterine lining, and rounds out Flow tea's flavor with brightness against the warmth of ginger and cinnamon-adjacent spice notes.
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According to PubMed: Sivaslioglu & Goktas, Nutr Res Rev 2024, DOI: 10.1017/S0954422424000350
"Every ingredient earns its place in the blend because of what's been studied about it, not because it's trending."
The CINIS formulation standard
Rebuild Tea
This is for when you're feeling like yourself again: your energy's back, your mood's better, and you're actually excited to make plans. That's your estrogen starting to rise as your body rebuilds after your period, restocking the minerals it lost along the way. Rebuild tea works with that, giving your body a hand so the comeback actually sticks.
Spearmint
A clinical trial in women with hirsutism found that drinking spearmint tea twice daily for five days significantly lowered free testosterone while increasing LH, FSH, and estradiol, one of the more specific hormonal findings in herbal tea research.
Why here: as estrogen begins its rise during the follicular phase, spearmint supports a healthy, balanced ratio of androgens to estrogen, the same shift linked to clearer, calmer skin, which is why we included it here.
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According to PubMed: Akdoğan et al., Phytother Res 2007, DOI: 10.1002/ptr.2074
Nettle Leaf
A scoping review of herbal teas used in women's health identifies nettle among the plants with the most consistent traditional use for this purpose, prized for its dense mineral and polyphenol content.
Why here: nettle's iron and mineral density supports the body as it rebuilds following menstrual blood loss, right as the follicular phase begins.
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According to PubMed: Poswal et al., Plant Foods Hum Nutr 2019, DOI: 10.1007/s11130-019-00750-w
Fennel Seed
In an 80-person randomized trial, fennel capsules significantly reduced menstrual pain severity and shortened period duration over three months. A separate randomized trial found fennel infusion significantly reduced the number of days between periods in women with irregular cycles.
Why here: fennel is traditionally used to ease bloating and support a flatter stomach as your body recovers from your period, and its documented effect on cycle regularity fits the follicular phase timing too.
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According to PubMed: Ghodsi & Asltoghiri, J Pediatr Adolesc Gynecol 2014, DOI: 10.1016/j.jpag.2013.12.003; Mokaberinejad et al., J Obstet Gynaecol 2019, DOI: 10.1080/01443615.2018.1541232
Butterfly Pea Flower
Known for its deep blue anthocyanin pigment, butterfly pea flower shows antioxidant, anti-inflammatory, and hepatoprotective activity in laboratory research. A 2025 review notes most findings are still preclinical.
Why here: adds antioxidant support during the follicular phase's high cell-turnover window, as the body prepares a new egg for release, and gives Rebuild tea its signature color shift.
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According to PubMed: Maia et al., Plants (Basel) 2025, DOI: 10.3390/plants14213322
20 ingredients. 4 phases. 0 guesswork.
Every citation sourced directly from PubMed
Beauty Tea
This is for when you're feeling confident, radiant, and that girl! You're the best version of you right now, and it's not in your head. Your estrogen is at its peak. Beauty tea works with that: clear skin, a natural glow, and a little help clearing out the hormones your body's already done using.
Milk Thistle Seed
A 2025 meta-analysis of 55 randomized trials (3,545 patients) found silymarin, milk thistle's active compound, produced a statistically significant reduction in liver enzymes AST and ALT, among the most well-supported hepatic-support botanicals in the literature, with effects strongest at doses under 400mg.
Why here: as estrogen peaks at ovulation, the liver is doing its heaviest work metabolizing and clearing it, milk thistle supports that clearance process directly.
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According to PubMed: Shahsavari et al., BMC Complement Med Ther 2025, DOI: 10.1186/s12906-025-04886-y
Dandelion Root
A comprehensive phytochemical review documents dandelion's traditional use for liver and digestive support, with diuretic, choleretic, and antioxidant properties identified in preclinical research.
Why here: works alongside milk thistle to support the body's natural process of clearing spent estrogen after ovulation, and eases the bloating some feel at mid-cycle.
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According to PubMed: Schütz et al., J Ethnopharmacol 2006, DOI: 10.1016/j.jep.2006.07.021
Schisandra Berry
Recognized in traditional Chinese medicine as an adaptogen, schisandra shows anti-inflammatory, antioxidant, and liver-protective activity across a 2025 review of its pharmacology, with particular relevance to stress-related fatigue.
Why here: buffers the stress load that can spike around ovulation, when hormonal shifts are fastest, and supports the same liver pathway as milk thistle and dandelion.
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According to PubMed: Bao et al., EPMA J 2025, DOI: 10.1007/s13167-025-00424-5
Hibiscus Flower
A six-month randomized, double-blind trial found daily hibiscus drink significantly lowered blood pressure, significantly raised multiple antioxidant markers, and significantly improved skin redness and moisture in participants.
Why here: estrogen's ovulatory peak is when skin naturally looks its best, hibiscus's measured effect on skin moisture and redness supports and extends that natural glow.
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According to PubMed: Chiu et al., J Food Biochem 2022, DOI: 10.1111/jfbc.14287
Every ingredient we use is organic, and our manufacturing partner is already USDA Organic certified.
CINIS's own certification is currently in process
Relief Tea
This is for when you're feeling the PMS creep in: everything your partner says annoys you, nothing's going your way, and you just feel off. That's real, and there's a reason: your progesterone drops hard the week before your period, which can leave you more stressed out and a lot less patient than usual. Relief tea is here to help you get through that week feeling calmer, not like you're one text away from losing it.
Lemon Balm
A 3-week randomized, double-blind trial in 100 adults found lemon balm supplementation significantly improved depression, anxiety, stress, and sleep scores (all P < 0.001). A separate 8-week randomized trial found a significant reduction in sleep disturbance specifically (P < 0.05).
Why here: eases the anxiety and sleep disruption that often surface as progesterone falls in the days before your period.
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According to PubMed: Bano et al., Front Pharmacol 2023, DOI: 10.3389/fphar.2023.1250560; Haybar et al., Clin Nutr ESPEN 2018, DOI: 10.1016/j.clnesp.2018.04.015
Passionflower
In a placebo-controlled crossover study, drinking passionflower tea itself, the exact preparation used in CINIS, produced significantly better subjective sleep quality ratings than placebo tea over a week of use (P < 0.01).
Why here: targets the sleep quality most disrupted in the luteal phase, when progesterone withdrawal and PMS symptoms most commonly interfere with rest.
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According to PubMed: Ngan & Conduit, Phytother Res 2011, DOI: 10.1002/ptr.3400
Holy Basil
A placebo-controlled trial found daily holy basil extract produced a statistically significant improvement in reaction time and error rate on cognitive stress tests compared with placebo over 30 days.
Why here: supports mental clarity and stress resilience during the luteal phase, when cortisol sensitivity is highest and focus can feel harder to hold onto.
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According to PubMed: Sampath et al., Indian J Physiol Pharmacol 2015, PMID: 26571987
Cinnamon
Two randomized, double-blind trials in the same population found cinnamon capsules significantly reduced menstrual pain severity and duration compared with placebo (P < 0.001), and one of the two also found a significant reduction in menstrual bleeding volume (P < 0.05).
Why here: helps address the carb cravings that tend to intensify in the days before your period, alongside its studied effect on cramping.
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According to PubMed: Jaafarpour et al., J Clin Diagn Res 2015, DOI: 10.7860/JCDR/2015/12084.5783; Jaafarpour et al., Iran Red Crescent Med J 2015, DOI: 10.5812/ircmj.17(4)2015.27032
Cardamom Seeds
A double-blind randomized trial in 194 women found green cardamom supplementation significantly lowered inflammatory markers TNF-α, IL-6, and CRP over four months (all P < 0.001), alongside improvements in androgen hormone levels.
Why here: supports digestion and calms the low-grade inflammation that tends to rise alongside PMS symptoms in the days leading up to your period.
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According to PubMed: Cheshmeh et al., Eat Weight Disord 2021, DOI: 10.1007/s40519-021-01223-3
Nettle Leaf
As in Rebuild tea, nettle contributes mineral density and a strong history of traditional use in herbal tea blends for women's health, documented in scoping review literature.
Why here: replenishes minerals ahead of the blood loss that begins with the next cycle, giving the body a head start heading into menstruation.
› View study
According to PubMed: Poswal et al., Plant Foods Hum Nutr 2019, DOI: 10.1007/s11130-019-00750-w
How we chose this research
Every study referenced on this page was retrieved directly from PubMed, the National Library of Medicine's database of peer-reviewed biomedical research. Where evidence for an ingredient is strong, multiple randomized trials or a meta-analysis, we say so. Where it's early, preclinical, or based on traditional use alone, we say that too.
This page will be updated as new research is published.
Obsessed with quality, always
CINIS is formulated by a Doctor of Pharmacy, sourcing and transparency standards aren't an afterthought, they're the starting point.
Organic-grown ingredients
Every ingredient in our formulations is organically grown. We select single-origin botanicals and avoid fillers, artificial colors, and synthetic flavor carriers.
USDA Organic, in process
Every ingredient we use is organic, and our manufacturing partner is already USDA Organic certified. We're now completing certification for CINIS itself, so you'll soon see it on the label too.
Pharmacist-reviewed ratios
Every blend composition is reviewed for ingredient interactions and dosing plausibility relative to the published research above.
